Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity connected with bortezomib, a proteasome inhibitor Utilized in the procedure of multiple myeloma. Its synthesis or study is very important for guaranteeing the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound during the synthesis of imatinib, a drug that targets distinct kinds of most cancers, which includes Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their research is crucial for optimizing the creation system and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to treat breast most cancers, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the treatment of breast CAS NO. 155405-80-4 cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the procedure of colorectal cancer and smaller cell lung cancer.
three-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved in the synthesis of adamantane derivatives, that have a variety of programs, together with antiviral Qualities.
Vildagliptin Intermediates: Used in the GeMcitabine Intermediate 8 production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-4 to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of various gluconic acid derivatives, which can be used in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication used to manage sort 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).